Mega Omega Description
Long chain omega-3 fatty acids are important components of membranes within organs and tissues. Supplementation with omega-3 fatty acids is well established as a way to improve cardiovascular health and a number of other functions within the body.
Mega Omega Ingredients
Omega 3 Fatty Acids:
• Essential fatty acids found in certain seeds, vegetables, and fish.
• The conversion of LNA to EPA and DHA is blocked or slowed in many humans, supplementation of EPA and DHA is more efficient.
• Study evaluating fish consumption and the risk of CHD in men, found the risk of coronary heart disease is reduced as much as 50% in men who
consume 30 grams of fish per day.
• 11,000 patients surviving a recent myocardial infarction were randomly given 1g/day omega 3 fatty acids, 300mg of vitamin E, both or placebo. The
group receiving omega 3 fatty acids had a significantly reduced rate of cardiovascular mortality as early as 3 and 4 months. Dramatic reduction rates
in sudden deaths were achieved after 9 months.
• Long chain fatty n-3 acids from fish have been shown to be beneficial in lowering triglycerides . A meta-analysis of 65 reports showed triglyceride levels
were reduced an average of 25% in those who consumed fish oil (average consumption 4g/ day EPA+DHA).
• A meta-analysis of 31 placebo-controlled trials documenting the effects of n-3 fatty acids on blood pressure, found that omega-3 fatty acids from fish
had an average reduction rate of -0.66/-0.35 mm Hg/gram of omega-3 fatty acids.
• Study investigating the effects of n-3 fatty acids on Wistar rats with metabolic syndrome, found after administration of fish oil (EPA+DHA) for 6 weeks,
the rats had a significant reduction in blood pressure, serum insulin, triacylglycerols, cholesterol, free fatty acids and total lipids.
• EPA competes with arachidonic acid (AA) for enzymatic metabolism (COX,LOX), reducing inflammatory responses.
• There have been successful results among patients with rheumatoid arthritis using omega-3 fatty acids from fish oil. Meta-analysis data suggest
improvements in tender joints and morning stiffness. The most significant benefits were seen in trials using 2.6 grams/day, 30 mg/kg/day and 40 mg/
• Fish oils have also been examined in patients with inflammatory bowel diseases including ulcerative colitis and Crohn’s disease. A number of clinical
trials have shown that doses up to 4.5 and 5.4 grams per day have some benefit on preventing relapses, but can reduce the dependence on steroid
Additional Cardiovascular benefits:
• NO-induced endothelial relaxation
• Reducing atherogenic adhesion molecules
• Stabilizing atherosclerotic plaques
• EPA and DHA from fish oil are the most potent immunomodulatory agents among the fatty acids.
• In a study looking at the correlation between depression and omega-3 fatty acids, a sample of 3,204 adults were examined. Level of depression was
estimated with the 21-item Beck Depression Inventory. Mild to severe depressive symptoms were more prevalent among women who consumed fish
less than once a week than women who consumed fish more than once a week, a similar trend was observed in men.
• Rapid growth of the brain occurs during the last trimester of pregnancy and several months after birth. DHA is crucial for this development, fetal and
newborn fatty acid metabolism is inadequate to provide proper levels of DHA. Maternal supplementation of DHA during the third trimester and while
breastfeeding has been shown to improve cognitive development in newborns.
As a Dietary Supplement, 1 softgel capsule per day.
American Heart Association Recommendation:
• Patients with documented Coronary Heart Disease (CHD) consume about 1 gram (1-2 capsules) of EPA + DHA per day, preferably from fatty fish.
• Patients who need to lower triglycerides consume 2 to 4 grams (3-6 capsules) of EPA+ DHA per day provided as dietary supplement under a
• Arterial compliance
• Reduced asymmetric dimethyl arginine (ADMA)
• Peroxisome proliferators-activated receptors (PPAR) regulation.